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Number: GOG 264 Principal Investigator: Mutch, David
Title: A Randomized Phase II Trial of Paclitaxel and Carboplatin vs. Bleomycin Etoposide, and Cisplatin for Newly Diagnosed Advanced Stage and Recurrent Chemonaive Sex Cord-Stromal Tumors of the Ovary
Phase: II Disease Site: Ovary
Participating Site(s):
 
 
Contact: 800-600-3606 or info@ccadmin.wustl.edu

Description:
The purpose of this study is to find out whether treatment with drugs paclitaxel and carboplatin work better to control your cancer than treatment with the drugs bleomycin, etoposide and cisplatin, which is the standard treatment for your type of cancer. Another purpose of this study is to find out what side effects are caused by treatment with these drug combinations. Another purpose of this study is to examine whether inhibin levels (a blood test) might be a good way to know how someone is responding to treatment. In this study you will get paclitaxel and carboplatin (considered the experimental therapy) or bleomycin, etoposide and cisplatin (considered the standard therapy).

Additionally, more will be learned about this specific type of rare ovarian cancer by studying certain markers and substances.
 
More Information:
Internal Protocol Documents (requires Siteman administrative database password)