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Number: 201104354 Principal Investigator: Govindan, Ramaswamy
Title: A Phase 1 study of BAY 80-6946 (phosphatidylinositol 3 - kinase inhibitor) in combination with paclitaxel in subjects with advanced solid malignancy
Phase: I Disease Site: Multiple Sites
Participating Site(s):
 
Main Campus
Map and Directions
 
Contact: 800-600-3606 or info@ccadmin.wustl.edu

Description:
The purpose of this study is to find the highest and safest dose of an investigational drug called BAY 80-6946 in
combination with paclitaxel, determine the side effects of a weekly dosing, determine how much BAY 80-6946 is in the blood at specific times after administration, determine if this combination of medications cause tumor shrinkage, and find out if biomarkers of BAY 80-6946 have predicted response to the combination therapy(Does the study drug affect your tumor in the way we think it does?).
 
More Information:
ClinicalTrials.gov #
Internal Protocol Documents (requires Siteman administrative database password)