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Number: 201304130 Principal Investigator: Lockhart, A. Craig
Title: A Phase 1B, Open-Label, Dose-Escalation, Multi-arm Study of MLN4924 Plus Docetaxel, Gemcitabine, or Combination of Carboplatin and Paclitaxel, in Patients with Solid Tumors (C15010)
Phase: I Disease Site: Multiple Sites
Participating Site(s):
 
Main Campus
Map and Directions
 
Contact: 800-600-3606 or info@ccadmin.wustl.edu

Description:
The main purposes of this research study are to determine:
• The discomforts and risks of MLN4924 in combination with docetaxel, paclitaxel and
carboplatin, or gemcitabine
• The highest dose of MLN4924 in combination with other standard treatments that can be given to patients without causing discomforts and risks that are too severe
• How much MLN4924, in combination with other standard treatments is absorbed into the
bloodstream and eliminated from the body
• How MLN4924 in combination with other standard treatments affects targets in tumor cells and tumor growth
 
More Information:
Ct.gov entry
Internal Protocol Documents (requires Siteman administrative database password)