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Number: 201402026 Principal Investigator: Waqar, Saiama
Title: A Randomized, Double-Blind Phase 2 Study of Ruxolitinib or Placebo in Combination with Pemetrexed/Cisplatin and Pemetrexed Maintenance for Initial Treatment of Subjects with Nonsquamous Non-Small cell Lung Cancer That is Stage IIIB with Pleural/Pericardial Effusion, Stage IV or Recurrent
Phase: II Disease Site: Lung
Participating Site(s):
 
Main Campus
Map and Directions
 
Contact: 800-600-3606 or info@ccadmin.wustl.edu

Description:
There are two parts to this study; the main purpose of Part 1 of this study is to determine a dose of
ruxolitinib that is safe, effective and tolerable in combination with pemetrexed/cisplatin. The main purpose
of Part 2 of this study is to find out if taking ruxolitinib when given in combination with pemetrexed/cisplatin is better than taking a placebo in combination with pemetrexed/cisplatin.
 
More Information:
ClinicalTrials.Gov Link
Internal Protocol Documents (requires Siteman administrative database password)