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CLINICAL TRIAL SEARCH RESULTS

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 Number: 201404139 Principal Investigator: Adkins, Douglas
Title: Phase I/II Trial of the Addition of PD 0332991 to Cetuximab in Patients with Incurable SCCHN
Description: The purpose of this research study is to find the maximum tolerated dose of a drug called palbociclib when given in combination with a drug called cetuximab, and to evaluate the side effects of this combination and look at how effective it is....MORE
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 Number: 201211110 Principal Investigator: Adkins, Douglas
Title: A Phase I Trial of Pazopanib Suspension plus Cetuximab in Patients with Incurable Head and Neck Squamous Cell Carcinoma
Description: The purpose of this research study is to find the best dose of the study drug (pazopanib) in combination with cetuximab, as well as to see what the side effects of this treatment regimen are in patients with head and neck cancer....MORE
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 Number: 201207059 Principal Investigator: Haughey, Bruce
Title: Adjuvant De-escalation, Extracapsular Spread, P16+, Transoral (A.D.E.P.T) Trial for Oropharhynx Malignancy
Description: This research study is looking at cancer of the oropharynx (tonsil and/or base of the tongue) which has been shown to be related to the human papillomavirus (HPV) and which has lymph nodes showing extracapsular spread, meaning that the cancer in the lymph nodes is exposed to the soft tissue around ...MORE
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 Number: 201205124 Principal Investigator: Uppaluri, Ravindra
Title: A Phase II Window of Opportunity Trial with GSK1120212 in Surgically Resectable Oral Cavity Squamous Cell Cancer
Description: The purpose of this research study is test the investigational drug GSK1120212 over the course of the two weeks prior to your surgery to see whether the treatment results in any changes to your tumor....MORE
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 Number: P2C 9165 Principal Investigator: Adkins, Douglas
Title: NCI 9165 / UC 12-1359: A randomized phase II trial of ARQ 197 (tivantinib)/cetuximab versus cetuximab in patients with recurrent/metastatic head and neck cancer
Description: The purpose of this study is to test how well cetuximab alone or in combination with ARQ197 (tivantinib) are able to treat head and neck squamous cell carcinomas that have recurred or are metastatic....MORE
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 Number: 201102048 Principal Investigator: Adkins, Douglas
Title: Randomized Double- Blind Phase II Trial of Everolimus Versus Placebo as Adjuvant Therapy in Patients with Locally Advanced Squamous Cell Cancer of the Head and Neck (SCCHN)
Description: The purpose of this clinical research study is to see if Everolimus helps keep head and neck cancer from coming back after patients complete regular treatment....MORE
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 Number: RTOG 0920 Principal Investigator: Thorstad, Wade
Title: A Phase III Study of Postoperative Radiation Therapy (IMRT) +/- Cetuximab For Locally Advanced Resected Head and Neck Cancer
Description: The purpose of this study is to compare the effects, good and/or bad, of radiation therapy alone with radiation therapy and cetuximab on you and your cancer to find out which is better. In this study, you will get either radiation therapy alone OR radiation therapy and cetuximab. If you participate...MORE
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 Number: 201404050 Principal Investigator: Adkins, Douglas
Title: Phase II multicenter randomized, double blind, placebo controlled study assessing the efficacy of buparlisib (BKM120) plus paclitaxel vs. placebo plus paclitaxel in patients with platinum pre-treated recurrent or metastatic head and neck squamous cell carcinoma
Description: The purpose of this research study is to find out if the drug buparlisib in combination with paclitaxel is safe and has beneficial effects in patients who have recurrent or metastatic head and neck squamous cell carcinoma....MORE
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 Number: 201401078 Principal Investigator: Adkins, Douglas
Title: A phase Ib dose escalation/randomized phase II, multicenter, open-label study of BYL719 in combination with cetuximab in patients with recurrent or metastatic head and neck squamous cell carcinoma
Description: The purpose of this research study is to find out if the combination treatment of cetuximab and BYL719 is safe and has a beneficial effect in patients with head and neck cancer....MORE
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 Number: 201308079 Principal Investigator: Adkins, Douglas
Title: A Randomized, Double-Blind, Placebo-Controlled Study of Chemotherapy Plus Cetuximab in Combination with VTX-2337 in Patients with Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
Description: The purpose of this research study is to compare the standard treatment to VTX-2337 added to the standard treatment to see if it helps tumors stop growing or shrink, and if it helps patients with squamous cell cancer of the head and neck live longer....MORE
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 Number: 201305133 Principal Investigator: Adkins, Douglas
Title: A Phase 1b, open-label, multi-center, dose escalation study of the safety, tolerability, pharmacodynamic and pharmacokinetic properties of intravenous GC4419 in combination with radiation and chemotherapy for squamous cell cancers of the head and neck
Description: The purpose of this study is to find out if an investigational drug called GC4419 can be used to prevent or decrease mouth pain and ulcers, which may be caused by cancer treatment....MORE
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 Number: ACRIN 6685 Principal Investigator: Nussenbaum, Brian
Title: PET/CT Staging of Head and Neck Cancer and its Impact on the N0 Neck Surgical Treatment
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 Number: 201310141 Principal Investigator: Adkins, Douglas
Title: A Double-Blind, Randomized, Placebo-Controlled, Dose-Escalating, Multicenter Study of SGX942 for the Attenuation of Oral Mucositis in Patients Being Treated with Concomitant Chemoradiation (CRT) for the Treatment of Squamous Cell Carcinoma of the Head and Neck
Description: The purpose of this research study is to find out what effects, good and /or bad, of a drug called SGX942 compared to placebo has on you and any resulting oral mucositis you may develop as a result of chemoradiation therapy....MORE
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 Number: 201110089 Principal Investigator: Haughey, Bruce
Title: Observational Study of Swallowing Function after Treatment of Advanced Laryngeal Cancer
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 Number: 201102323 Principal Investigator: Gay, Hiram
Title: Analysis of Histological, Genomic, Molecular, and Clinical Factors in Head and Neck Cancer: The Tissue Acquisition Protocol (TAP)
Description: The purpose of this research study is to discover genetic changes associated with cancer by documenting the DNA changes that occur in head and neck cancer cells. This may lead to better ways of preventing, detecting, and treating cancer and perhaps other diseases as well....MORE
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 Number: 201111208 Principal Investigator: El-Mofty, Samir
Title: HPV-related squamous cell carcinoma of the head and neck skin in kidney transplant patients
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 Number: 201110274 Principal Investigator: Lewis Jr., James
Title: Genetic Markers of Prognosis in HPV-Related Oropharyngeal Squamous Cell Carcinoma
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 Number: 201107372 Principal Investigator: Chernock, Rebecca
Title: Evaluation of proliferative verrucous leukoplakia (PVL) lesions for viral genomic sequences
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 Number: 201105387 Principal Investigator: Haughey, Bruce
Title: Data Collection for Minimally Invasive, Endoscopic Head and Neck Cancer Surgery at Barnes-Jewish Hospital
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 Number: 201104011 Principal Investigator: Lewis Jr., James
Title: HPV and Tumor Protein Expression in Histologic Variants of Squamous Cell Carcinoma of the Head and Neck
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