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CLINICAL TRIAL SEARCH RESULTS

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 Number: 201201124 Principal Investigator: Linehan, David
Title: Phase IB Study of FOLFIRINOX and PF-04136309 in Patients with Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma
Description: The purpose of this research study is to find the best dose of the study drug (PF-04136309) in combination with FOLFIRINOX as well as to see what the side effects of this treatment regimen are. PF-04136309 is considered investigational, which means that it has not been approved by the U.S. Food and ...MORE
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 Number: CALGB S1115 Principal Investigator: Wang-Gillam, Andrea
Title: Randomized Phase II Clinical Trial of AZD6244 Hydrogen Sulfate (NSC-748727) and MK-2206 (NSC-749607) vs. mFOLFOX in Patients with Metastatic Pancreatic Cancer after Prior Chemotherapy
Description: The purpose of this study is to find out what effects, good and/or bad, the combination of MK-2206 and AZD6244 hydrogen sulfate or a standard combination of oxaliplatin and fluorouracil has on metastatic pancreatic cancer...MORE
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 Number: 201401025 Principal Investigator: Wang-Gillam, Andrea
Title: A Phase 2B, Randomized, Controlled, Multicenter, Open-Label Study of the Efficacy and Immune Response of GVAX Pancreas Vaccine (with Cyclophosphamide) and CRS-207 Compared to Chemotherapy or to CRS-207 Alone in Adults with Previously-Treated Metastatic Pancreatic Adenocarcinoma
Description: The purpose of this research study is to test whether GVAX pancreas vaccine and CRS-207 together are safe and work better than chemotherapy to treat patients with advanced pancreatic cancer who have received at least one prior chemotherapy treatment for cancer that has spread beyond the pancreas....MORE
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 Number: 201310160 Principal Investigator: Wang-Gillam, Andrea
Title: An Open-Label, Phase I Dose Escalation Trial of TH-302 in Combination with Gemcitabine and Nab-Paclitaxel in Previously Untreated Subjects with Metastatic or Locally Advanced Unresectable Pancreatic Adenocarcinoma
Description: The purpose of this research study is to investigate the safety of the study drug TH-302 in combination with two other chemotherapy drugs in patients with advanced pancreatic cancer who have not been treated before, and to find out the best dose to further test the study drug....MORE
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 Number: 201304099 Principal Investigator: Wang-Gillam, Andrea
Title: A Phase 2, Randomized, Multicenter Study of PEGPH20 (PEGylated Recombinant Human Hyaluronidase) Combined with nab-Paclitaxel Plus Gemcitabine Compared With nab-Paclitaxel Plus Gemcitabine in Subjects With Stage IV Previously Untreated Pancreatic Cancer
Description: There are two parts to this study. The purpose of both parts is to evaluate PEGPH20 at a dose of 3.0 µg/kg in combination with 2 chemotherapy drugs (a standard dose of gemcitabine plus a dose of nab-paclitaxel that has been tested in pancreatic cancer patients) versus gemcitabine and nab-paclitaxel ...MORE
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 Number: 201103016 Principal Investigator: Mullady, Daniel
Title: The Clinical Impact of Immediate On-site Cytopathology Evaluation during Endoscopic Ultrasound-Guided Fine Needle Aspiration of Pancreatic Mass: A Multicenter, Prospective Randomized Controlled Trial
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 Number: 201109243 Principal Investigator: Linehan, David
Title: 30-day readmission following pancreatectomy: a root-cause analysis
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 Number: 201105335 Principal Investigator: Strasberg, Steven
Title: Whipple at the Splenic Artery: A Procedure for Ductal Adenocarcinoma of the Pancreas with Extensive Involvement of the Porto-Mesenteric Axis: A Registry Study
Description: The main purpose of this study is to determine whether the standard surgical procedure used to remove pancreas tumors (called a Whipple procedure) is effective and safe in removing tumors located near or on the major veins that drain the intestine and spleen and supply blood to the liver. The abbrev...MORE
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 Number: 201210092 Principal Investigator: Collins, Brian
Title: Endoscopic Ultrasound Fine Needle Aspiration Biopsy of Serous Cystadenoma of Pancreas
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 Number: 201106347 Principal Investigator: Wang-Gillam, Andrea
Title: A Pilot Study of Evaluation of a Phosphorylation Signature from Pancreatic Cancer Tumors
Description: The main purpose of this study is to see if we can use blood samples and tissue samples from a fine needle aspiration of pancreas tumors to detect proteins that are crucial for pancreatic cancer development. The study will also determine the impact of those proteins on patients with pancreatic canc...MORE
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 Number: 201103202 Principal Investigator: Wang-Gillam, Andrea
Title: Construction of Pancreatic Cancer Tissue and Stroma Array
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 Number: 201212015 Principal Investigator: Hawkins, William
Title: Frozen Section Neck Margin in Pancreatic Adenocarcinoma
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 Number: 201108327 Principal Investigator: Wang-Gillam, Andrea
Title: Phase I Study of Erlotinib and Temsirolimus in Resistant Solid Malignancies
Description: The purpose of this study is to determine the maximum tolerated dose and side effects of the combination of two drugs, temsirolimus and erlotinib, used to treat solid tumor cancers. Temsirolimus is approved by the Food and Drug Administration (FDA) for treatment of renal cancer and is considered inv...MORE
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 Number: 201107068 Principal Investigator: Lockhart, A. Craig
Title: Phase I Safety and Pharmacokinetic Study of XRP6258 (Cabazitaxel) In Advanced Solid Tumor Patients with Varying Degrees of Hepatic Impairment
Description: The purpose of this study is to determine if Cabazitaxel is a safe treatment for patients with advanced cancers of different types who also have different levels of liver dysfunction. The highest safe dose of cabazitaxel (the maximum tolerated dose, or MTD) that can be given to patients with your le...MORE
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