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CLINICAL TRIAL SEARCH RESULTS

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 Number: 201011804 Principal Investigator: Fontana, Luigi
Title: Does Protein Restriction Inhibit Prostate Cancer Growth?
Description: The purpose of this study is to test the hypothesis that a low protein diet will inhibit prostate cancer growth. We propose to study two groups of prostate cancer patients: 38 men scheduled to undergo radical prostatectomy, and 44 men with persistently elevated prostate-specific antigen (PSA) after ...MORE
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 Number: RTOG 1115 Principal Investigator: Michalski, Jeff
Title: Phase III Trial of Dose Escalated Radiation Therapy and Standard Androgen Deprivation Therapy (ADT) with A GNRH Agonist vs. Dose Escalated Radiation Therapy and Enhanced ADT with a GNRH Agonist and TAK-700 for Men with High Risk Prostate Cancer
Description: The purpose of this study is to compare the effects of hormone therapy (androgen deprivation) and TAK-700 plus radiation therapy with hormone therapy (androgen deprivation)and radiation therapy on you and your prostate cancer to find out which therapy is better. TAK-700 is an experimental drug, whi...MORE
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 Number: RTOG 0924 Principal Investigator: Michalski, Jeff
Title: Androgen Deprivation Therapy and High Dose Radiotherapy With or Without Whole-Pelvic Radiotherapy in Unfavorable Intermediate or Favorable High Risk Prostate Cancer: A Phase III Randomized Trial
Description: The purpose of this study is to compare the effects of hormone therapy (androgen deprivation) and radiation therapy to the prostate gland and seminal vesicles with hormone therapy and radiation therapy to the whole pelvic body area on you and your prostate cancer to find out which is better. There ...MORE
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 Number: RTOG 0815 Principal Investigator: Michalski, Jeff
Title: A Phase III Prospective Randomized Trial of Dose-Escalated Radiotherapy With or Without Short-Term Androgen Deprivation Therapy For Patients With Intermediate-Risk Prostate Cancer
Description: The purpose of this study is to compare the effects of dose-escalated radiation therapy with or without hormone therapy on prostate cancer. Prior studies have suggested possible advantages to the administration of hormonal therapy with radiation. However, those studies were performed with radiation...MORE
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 Number: RTOG 0534 Principal Investigator: Michalski, Jeff
Title: A Phase III Trial of Short Term Androgen Deprivation with Pelvic Lymph Node or Prostate Bed Only Radiotherapy (SPPORT) in Prostate Cancer Patients with a Rising PSA After Radical Prostatectomy
Description: The purpose of this study is to compare the effects, good and/or bad of three standard of care treatment methods on participants and their cancer. External beam radiation therapy is one of the standard treatments for men with prostate cancer who have a rising PSA after surgery. Different method...MORE
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 Number: CALGB S1216 Principal Investigator: Picus, Joel
Title: A Phase III Randomized Trial Comparing Androgen Deprivaton Therapy + TAK-700 with Androgen Deprivation Therapy + Bicalutamide in Patients with newly Diagnosed Metastatic Hormone Sensitive Prostate Cancer (S1216)
Description: The purpose of this study is to find out what effects there are to adding the new investigational drug TAK-700 to standard hormone therapy which is used to treat prostate cancer as compared to the standard of hormone therapy alone....MORE
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 Number: CALGB A031201 Principal Investigator: Picus, Joel
Title: Phase III Trial of Enzalutamide (NSC # 766085) Versus Enzalutamide, Abiraterone and Prednisone for Castration Resistant Metastatic Prostate Cancer
Description: The purpose of this study is to compare the effects, good and/or bad, of abiraterone, prednisone, and enzalutamide with enzalutamide alone on patients who have prostate cancer to find out which is better....MORE
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 Number: CALGB 90203 Principal Investigator: Picus, Joel
Title: A Randomized Phase III Study of Neo-Adjuvant Docetaxel and Androgen Deprivation Prior to Radical Prostatectomy versus Immediate Radical Prostatectomy in Patients with High-Risk, Clinically Localized Prostate Cancer
Description: The purpose of this study is to compare the effects (good and bad) of the combination of chemotherapy and hormone therapy followed by radical prostatectomy (surgery to remove your prostate) with radical prostatectomy alone to see which is better. This research is being done because many men with...MORE
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 Number: 201208130 Principal Investigator: Picus, Joel
Title: A Randomized Phase 3 Study Comparing Cabazitaxel/Prednisone in Combination with Custirsen (OGX-011) to Cabazitaxel/Prednisone for Second-Line Chemotherapy in Men with Metastatic Castrate Resistant Prostate Cancer
Description: The purpose of this research study is to find out if being treated with cabazitaxel, prednisone and the experimental drug custirsen is better than cabazitaxel and prednisone alone at increasing survival in subjects with metastatic, castrate resistant prostate cancer. The study will also see if custi...MORE
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 Number: CALGB 70807 Principal Investigator: Strope, Seth
Title: The Men’s Eating and Living (MEAL) Study: A Randomized Trial of Diet to Alter Disease Progression in Prostate Cancer Patients on Active Surveillance
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 Number: 201110129 Principal Investigator: Figenshau, R. Sherburne
Title: A Double-blind, Placebo-controlled Study to Evaluate New or Worsening Lens Opacifications in Subjects with Non-metastatic Prostate Cancer Receiving Denosumab for Bone Loss due to Androgen-Deprivation Therapy
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 Number: 201108010 Principal Investigator: Wilson, Richard
Title: Germline Sequencing for Aggressive Prostate Carcinoma
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 Number: 201105154 Principal Investigator: Drake, Bettina
Title: Obesity and Vitamin D Related Effects on Prostate Cancer Recurrence
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 Number: 201108327 Principal Investigator: Wang-Gillam, Andrea
Title: Phase I Study of Erlotinib and Temsirolimus in Resistant Solid Malignancies
Description: The purpose of this study is to determine the maximum tolerated dose and side effects of the combination of two drugs, temsirolimus and erlotinib, used to treat solid tumor cancers. Temsirolimus is approved by the Food and Drug Administration (FDA) for treatment of renal cancer and is considered inv...MORE
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 Number: 201107068 Principal Investigator: Lockhart, A. Craig
Title: Phase I Safety and Pharmacokinetic Study of XRP6258 (Cabazitaxel) In Advanced Solid Tumor Patients with Varying Degrees of Hepatic Impairment
Description: The purpose of this study is to determine if Cabazitaxel is a safe treatment for patients with advanced cancers of different types who also have different levels of liver dysfunction. The highest safe dose of cabazitaxel (the maximum tolerated dose, or MTD) that can be given to patients with your le...MORE
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