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CLINICAL TRIAL SEARCH RESULTS

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 Number: 201407025 Principal Investigator: Van Tine, Brian
Title: A Randomized, Open-label, Phase II, Multi-center Trial of Gemcitabine (G) with Pazopanib (P) or Gemcitabine (G) with Docetaxel (T) in Previously Treated Subjects with Advanced Soft Tissue Sarcoma
Description: The purpose of this research study is to test the effectiveness and safety of Gemcitabine and Pazopanib compared with Gemcitabine and Docetaxel in participants with soft tissue sarcoma....MORE
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 Number: 201211010 Principal Investigator: Van Tine, Brian
Title: Phase 2 study of the mTOR inhibitor everolimus in combination with bevacizumab in patients with sporadic and neurofibromatosis type 1 (NF1) related refractory malignant peripheral nerve sheath tumors
Description: The purpose of this research study is to determine how well malignant peripheral nerve sheath tumors respond (experience tumor shrinkage or lack of further tumor growth) to treatment with everolimus in combination with bevacizumab....MORE
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 Number: CALGB A091202 Principal Investigator: Van Tine, Brian
Title: A Phase II Randomized, Double Blinded Study of the Peroxisome Proliferator-Activated Receptor Gamma Agonist, Efatutazone vs Placebo in Patients with Previously Treated, Unresectable Myxoid Liposarcoma
Description: The purpose of this study is to compare the safety and effects of efatutazone to using a placebo. ...MORE
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 Number: CALGB A091105 Principal Investigator: Van Tine, Brian
Title: A Phase III, Double Blind, Randomized, Placebo-Controlled Trial of Sorafenib in Desmoid Tumors or Aggressive Fibromatosis (DT/DF)
Description: The purpose of this study is to compare the effects, good and/or bad, of the drug sorafenib might have on the growth of desmoid tumors....MORE
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 Number: CALGB A091102 Principal Investigator: Van Tine, Brian
Title: Phase II Study of MLN8237 in Advanced/Metastatic Sarcoma
Description: The purpose of this study is to see the effects, good and/or bad, of the investigational drug MLN8237 on patients and their sarcoma....MORE
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 Number: 201411066 Principal Investigator: Van Tine, Brian
Title: An Open-Label Study to Evaluate the Pharmacokinetics of Doxorubicin following the Concomitant Intravenous Administration of Olaratumab (IMC-3G3) to Patients with Advanced Soft Tissue Sarcoma
Description: The purpose of this research study is to see how an investigational drug, olaratumab, affects the way doxorubicin is handled in people with advanced soft tissue sarcoma and how safe olaratumab is when given alone and in combination with doxorubicin....MORE
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 Number: 201410078 Principal Investigator: Van Tine, Brian
Title: Phase 2 Efficacy and Safety Study of Intravenous GPX-150, an Anthracycline Analog, in Patients with Soft Tissue Sarcoma
Description: The purpose of this research study is to test the safety and effectiveness of a drug called GPX-150 in patients with sarcoma....MORE
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 Number: 201408132 Principal Investigator: Van Tine, Brian
Title: A Multicenter, Randomized, Open-Label Phase 3 Study to Investigate the Efficacy and Safety of Aldoxorubicin Compared to Investigator’s Choice in Subjects with Metastatic, Locally Advanced, or Unresectable Soft Tissue Sarcomas Who Either Relapsed or Were Refractory to Prior Non-Adjuvant Chemotherapy
Description: The purpose of this research study is see if aldoxorubicin, an experimental drug, will slow the growth of your cancer when compared to other treatment for this type of cancer and to evaluate the side effects of the treatment...MORE
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 Number: 201202120 Principal Investigator: Van Tine, Brian
Title: A prospective, multicenter, randomized, open-label, active-controlled, two-parallel groups, phase 3 study to compare the efficacy and safety of masitinib to sunitinib in patients with gastrointestinal stromal tumor resistant to imatinib
Description: The purpose of this research study is to compare the efficacy and safety of a drug called masitinib to those of a standard treatment for GIST called sunitinib....MORE
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 Number: 201105233 Principal Investigator: Adkins, Douglas
Title: A Registry of Caris Life Sciences® Molecular Intelligence™ Service (Biomarker Assessment Results) Intended for for Correlation with Cancer Clinical Outcomes
Description: The purpose of this research is to create a repository for storing medical information so that it is available to investigators for use in future research studies....MORE
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