| Number: 201109179 |
Principal Investigator: Van Tine, Brian |
| Title: Determination of Tumor Response Rate by RECIST and FDG-PET Criteria to Dacarbazine in Metastatic Soft Tissue and Bone Sarcoma |
| Description: This study is for patients who have an advanced form of soft tissue or bone sarcoma that has spread to other parts of the body.
This study will evaluate the response to treatment and side effects of dacarbazine.
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| Number: 201209059 |
Principal Investigator: Wagner-Johnston, Nina |
| Title: Multisite randomized controlled trial of continuing vs. discontinuing statins |
| Description: The purpose of this study is to determine if discontinuing statin medications is safe and can reduce the burden of taking numerous medications. We anticipate that people with advanced illness will have less medicine-related side effects and symptoms if statins are discontinued, better quality of lif...MORE |
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| Number: CALGB A091103 |
Principal Investigator: Van Tine, Brian |
| Title: Phase II Study of the Angiopoietin-1 and -2 Peptibody AMG 386 For the Treatment of Angiosarcoma |
| Description: This phase II trial studies how well trebananib works in treating patients with advanced angiosarcoma that cannot be removed by surgery....MORE |
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| Number: CALGB A091102 |
Principal Investigator: Van Tine, Brian |
| Title: Phase II Study of MLN8237 in Advanced/Metastatic Sarcoma |
| Description: The purpose of this study is to see the effects, good and/or bad, of the investigational drug MLN8237 on patients and their sarcoma....MORE |
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| Number: 201202120 |
Principal Investigator: Van Tine, Brian |
| Title: A prospective, multicenter, randomized, open-label, active-controlled, two-parallel groups, phase 3 study to compare the efficacy and safety of masitinib to sunitinib in patients with gastrointestinal stromal tumor resistant to imatinib |
| Description: The purpose of this research study is to compare the efficacy and safety of a drug called masitinib to those of a standard treatment for GIST called sunitinib....MORE |
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| Number: 201109112 |
Principal Investigator: Van Tine, Brian |
| Title: A Randomized Controlled Study of YONDELIS (Trabectedin) or Dacarbazine for the Treatment of Advanced Liposarcoma or Leiomyosarcoma
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| Description: The purpose of this research study is to see if patients who take Yondelis have better overall survival compared to dacarbazine in patients who have advanced L-sarcoma who have previously been treated with an Anthracycline and Ifosfamide for this disease. The study will also measure the safety and ...MORE |
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| Number: 201109111 |
Principal Investigator: Van Tine, Brian |
| Title: A Randomized Phase 3, Multicenter, Open-Label Study Comparing TH-302 in Combination with Doxorubicin vs. Doxorubicin Alone in Subjects with Locally Advanced Unresectable or Metastatic Soft Tissue Sarcoma |
| Description: The purpose of this research study is to find out if an investigational drug called TH-302 can help patients with advanced soft tissue sarcoma when it is combined with doxorubicin. The purpose of this study is to gather information on the safety and effect on cancer of TH-302 in combination with dox...MORE |
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| Number: 201102472 |
Principal Investigator: Van Tine, Brian |
| Title: A Randomized, Open-label, Multicenter, Phase 3 Study to Compare the Efficacy and Safety of Eribulin with Dacarbazine in Subjects with Soft Tissue Sarcoma |
| Description: The purpose of this research study is to compare the safety and efficacy of eribulin and dacarbazine on patients with sarcoma. In this study patients will be treated with either eribulin or dacarbazine. They will not be treated with both....MORE |
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| Number: 201105233 |
Principal Investigator: Adkins, Douglas |
| Title: A Registry of Caris Target Now™ Test Results (Biomarker Expression Patterns) and Hematopoietic Diagnostics for Evaluation of Correlation with Clinical Outcomes for Cancer |
| Description: The purpose of this research is to create a repository for storing medical information so that it is available to investigators for use in future research studies....MORE |
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| Number: 201209121 |
Principal Investigator: Allman, Russell |
| Title: Location of lesion within the distal femur as a clue for distinguishing Giant cell tumor from aneurysmal bone cyst |
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