Number: HOG GU12-160 Principal Investigator: Picus, Joel
Title: A Randomized Phase 2 Study Comparing Docetaxel Alone to Docetaxel in Combination with OGX-427 in Patients with Relapsed or Refractory Metastatic Urothelial Carcinoma after Receiving a Platinum-containing Regimen
Description: The purpose of this study is to evaluate whether the combination of OGX-427 plus docetaxel will prolong the survival time of compared to docetaxel alone in patients with urothelial cancer whom are no longer responding to platinum-based chemotherapy treatment....MORE
 Number: RTOG 0926 Principal Investigator: Gay, Hiram
Title: A Phase II Protocol for Patients with Stage T1 Bladder Cancer to Evaluate Selective Bladder Preserving Treatment by Radiation Therapy Concurrent with Radiosensitizing Chemotherapy Following a Thorough Transurethral Surgical Re-Staging
Description: The purpose of this study is to find out the effects of transurethal surgery followed by radiation therapy plus chemotherapy....MORE
 Number: CTSU S1011 Principal Investigator: Grubb, III, Robert
Title: A Phase III Surgical Trial to Evaluate the Benefit of a Standard Versus an Extended Pelvic Lymphadenectomy Performed At Time of Radial Cystectomy For Muscle Invasive Urothelial Cancer
Description: The purpose of this study is to compare the effects, good and/or bad, of performing a standard lymph node removal versus an extended lymph node removal for patients with muscle invasive urothelial cancer....MORE
 Number: 201407150 Principal Investigator: Picus, Joel
Title: An Open-Label, Single-Arm, Phase 2 Study of Mocetinostat in Selected Patients with Inactivating Alterations of Acetyltransferase Genes in Previously Treated Locally Advanced or Metastatic Urothelial Carcinoma
Description: The main purpose of this study is to test whether patients with urothelial carcinoma with specific changes in the tumor genes benefit from treatment with mocetinostat....MORE
 Number: 201306057 Principal Investigator: Picus, Joel
Title: A Phase 1 Study of the Safety and Pharmacokinetics of Escalating Doses of AGS15E Given as Monotherapy in Subjects with Metastatic Urothelial Cancer
Description: The main purpose is to determine a safe dose of an invesigational drug, AGS15E, by testing the drug at different dose levels. The study will find out what effects, good and/or bad, it has on patients and their cancer....MORE
 Number: 201411135 Principal Investigator: Arora, Vivek
Title: Tissue, Blood, and Urine Acquisition for Genomic Analysis and Collection of Health Information for Patients with Malignancies of the Genitourinary Tract
 Number: 201405049 Principal Investigator: Govindan, Ramaswamy
Title: A Phase 1 Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-42756493, a pan-Fibroblast Growth Factor Receptor (FGFR) Tyrosine Kinase Inhibitor, in Subjects with Advanced or Refractory Solid Tumors or Lymphoma
Description: The purpose of this research study is to determine the effectiveness of the study drug, JNJ-42756493, on relapsed or refractory solid tumors....MORE