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CLINICAL TRIAL SEARCH RESULTS

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 Number: 201312115 Principal Investigator: Cashen, Amanda
Title: A phase II study of melphalan HCl for injection (propylene glycol-free), combined with carmustine, etoposide, and cytarabine (BEAM regimen) for myeloablative conditioning in lymphoma patients undergoing autologous stem cell transplantation
Description: The purpose of this research study is to determine the safety, side effects, and effectiveness of a new formulation of melphalan when it is administered as part of the BEAM regimen, which is given prior to stem cell transplant. BEAM is a 4-drug chemotherapy combination using the following drugs: car...MORE
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 Number: 201303012 Principal Investigator: Schroeder, Mark
Title: Phase I/II Trial of Intravenous Azacitidine in Patients Undergoing Matched Unrelated Stem Cell Transplantation
Description: This research study aims to discover the side effects and highest dose of a drug called azacitidine that can be given after a stem cell transplant to help prevent or minimize the effects of graft-versus-host disease (GVHD). We will also look at the way azacitidine might affect whether or how a pers...MORE
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 Number: 201211047 Principal Investigator: Schroeder, Mark
Title: A Pilot Study of Brentuximab Vedotin for the Prevention of Graft-Versus-Host Disease (GVHD) after Mismatched Unrelated Allogeneic Stem Cell Transplantation
Description: The purpose of this research study is discover the side effects and highest dose of a drug called brentuximab vedotin that can be given when receiving other drugs to help prevent or minimize the effects of graft-versus-host disease (GVHD)....MORE
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 Number: 201112026 Principal Investigator: Schroeder, Mark
Title: A Phase I/II Study Evaluating the Safety and Efficacy of Intravenous POL6326 for the Mobilization and Transplantation of HLA-Matched Sibling Donor Hematopoietic Stem Cells in Patients with Advanced Hematological Malignancies
Description: The purpose of this research study is to see whether donors who are treated with the new drug POL6326 are able to produce enough stem cells for transplant after one dose of the study drug (as compared to other drugs used for the same purpose, which may require multiple collections). We are also loo...MORE
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 Number: 201101864 Principal Investigator: Stockerl-Goldstein, Keith
Title: Autologous Followed by Non-myeloablative Allogeneic Transplantation for Non-Hodgkin's Lymphoma
Description: You may be invited to participate in a research study to treat non-Hodgkin’s lymphoma. The treatment plan consists of an autologous hematopoietic (blood) cell transplant followed by a non-myeloablative allogeneic transplantation (transplant from another individual). An autologous transplant is don...MORE
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 Number: 201102463 Principal Investigator: Fehniger, Todd
Title: KIR Genotyping for Unrelated Donor (URD) Selection Prior to Hematopoietic Cell Transplantation (HCT) for AML: Selecting a Favorable KIR Donor
Description: This study is investigating a newer donor selection factor, KIR genotyping, in addition to HLA testing and other donor selection factors....MORE
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 Number: BMT CTN 1102 Principal Investigator: Westervelt, Peter
Title: A Multi-Center Biologic Assignment Trial Comparing Reduced Intensity Allogeneic Hematopoietic Cell Transplant to Hypomethylating Therapy or Best Supportive Care in Patients Age 50 or Older with Intermediate-2 and High Risk Myelodysplastic Syndrome
Description: The purpose of this research study is to find out if a reduced-intensity transplant works better than the standard treatment for Myelodysplastic Syndrome (MDS). We also want to know how well you are able to do your normal activities after your treatment....MORE
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 Number: BMT CTN 0903 Principal Investigator: Westervelt, Peter
Title: Allogeneic Hematopoietic Cell Transplant for Hematological Cancers and Myelodysplastic Syndromes in HIV-Infected Individuals
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 Number: 201204060 Principal Investigator: Romee, Rizwan
Title: Randomized Phase III Trial of haploidentical HCT with or without an add back strategy of HSV-Tk donor lymphocytes in patients with high risk acute leukemia
Description: The purpose of this study is to determine if there is an increased in survival rate in patients who undergo a HCT transplantation followed by an infusion of genetically modified HSV-TK donor lymphocytes, compared to patients who have the standard HCT transplantation? with the standard infusion of he...MORE
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 Number: 201209074 Principal Investigator: Dubberke, Erik
Title: A Phase 3b Multi-Center, Double-Blind, Randomized, Placebo Controlled Study to Demonstrate the Safety and Efficacy of Fidaxomicin for Prophylaxis against Clostridium difficile-Associated Diarrhea in Adults Undergoing Hematopoietic Stem Cell Transplantation
Description: The purpose of this research study is to determine if fidaxomicin is safe and effective in the prevention of clostridium difficile-associated diarrhea, or CDAD, compared with placebo. As there is currently no other drug on the market used to prevent CDAD before it occurs, the information obtained fr...MORE
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 Number: BMT CTN 1202 Principal Investigator: Westervelt, Peter
Title: Prospective Multi-Center Cohort for the Evaluation of Biomarkers Predicting Risk of Complications and Mortality Following Allogeneic Hematopoietic Cell Transplant (HCT)
Description: The purpose of this study is to learn more about what makes related and unrelated (allogeneic) bone marrow, blood stem cell and umbilical cord blood transplants work well....MORE
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 Number: 201212113 Principal Investigator: Dubberke, Erik
Title: Evolution of CMV in Allogeneic Hematopoietic Cell Transplant Recipients
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