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CLINICAL TRIAL SEARCH RESULTS

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 Number: 201303012 Principal Investigator: Schroeder, Mark
Title: Phase I/II Trial of Intravenous Azacitidine in Patients Undergoing Matched Unrelated Stem Cell Transplantation
Description: This research study aims to discover the side effects and highest dose of a drug called azacitidine that can be given after a stem cell transplant to help prevent or minimize the effects of graft-versus-host disease (GVHD). We will also look at the way azacitidine might affect whether or how a pers...MORE
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 Number: 201211047 Principal Investigator: DiPersio, John
Title: A Pilot Study of Brentuximab Vedotin for the Prevention of Graft-Versus-Host Disease (GVHD) after Mismatched Unrelated Allogeneic Stem Cell Transplantation
Description: The purpose of this research study is discover the side effects and highest dose of a drug called brentuximab vedotin that can be given when receiving other drugs to help prevent or minimize the effects of graft-versus-host disease (GVHD)....MORE
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 Number: 201112026 Principal Investigator: DiPersio, John
Title: A Phase I/II Study Evaluating the Safety and Efficacy of Intravenous POL6326 for the Mobilization and Transplantation of HLA-Matched Sibling Donor Hematopoietic Stem Cells in Patients with Advanced Hematological Malignancies
Description: The purpose of this research study is to see whether donors who are treated with the new drug POL6326 are able to produce enough stem cells for transplant after one dose of the study drug (as compared to other drugs used for the same purpose, which may require multiple collections). We are also loo...MORE
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 Number: 201101864 Principal Investigator: Stockerl-Goldstein, Keith
Title: Autologous Followed by Non-myeloablative Allogeneic Transplantation for Non-Hodgkin's Lymphoma
Description: You may be invited to participate in a research study to treat non-Hodgkin’s lymphoma. The treatment plan consists of an autologous hematopoietic (blood) cell transplant followed by a non-myeloablative allogeneic transplantation (transplant from another individual). An autologous transplant is don...MORE
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 Number: 201011859 Principal Investigator: DiPersio, John
Title: A pilot study of GCSF +/- Plerixafor (AMD3100) mobilized donor CD34+ enriched peripheral blood mononuclear cells for the treatment of allogeneic stem cell transplant recipients with limited donor engraftment
Description: This study will evaluate if giving a “boost” of T-cell depleted, enriched stem cells (known as CD34+ cells) can improve patients' blood counts following an allogeneic stem cell transplant....MORE
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 Number: 201109177 Principal Investigator: Pusic, Iskra
Title: A Randomized Phase II Study of Imatinib and Rituximab for Cutaneous Sclerosis after Allogeneic Hematopoietic Cell Transplantation
Description: The purpose of this research study is to see if cutaneous sclerosis improves with the use of Rituximab or Imatinib....MORE
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 Number: 201104235 Principal Investigator: Pusic, Iskra
Title: Targeted Therapy of Bronchiolitis Obliterans Syndrome
Description: The purpose of this research study is to see if an investigational combination of three drugs is safe and effective in treating BOS after allogeneic hematopoietic cell transplant....MORE
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 Number: 201102463 Principal Investigator: Fehniger, Todd
Title: KIR Genotyping for Unrelated Donor (URD) Selection Prior to Hematopoietic Cell Transplantation (HCT) for AML: Selecting a Favorable KIR Donor
Description: This study is investigating a newer donor selection factor, KIR genotyping, in addition to HLA testing and other donor selection factors....MORE
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 Number: 201207064 Principal Investigator: Westervelt, Peter
Title: A Phase II Controlled Trial of a Single Prohema-CB unit(Ex Vivo Modulated Human Cord Blood Cells)As Part of a Double Umbilical Cord Blood Transplant Following Myeloablative or Reduced Intensity Conditioning For Patients Age 15-65 Years With Hematologic Malignancies
Description: The purpose of this research study is to determine the effects of the ProHema-CB treatment on umbilical cord blood units to be used in transplantation. ProHema-CB treatment is being tested to see if it can improve the ability of umbilical cord blood stem cells to grow after transplantation....MORE
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 Number: 201204060 Principal Investigator: DiPersio, John
Title: Randomized Phase III Trial of haploidentical HCT with or without an add back strategy of HSV-Tk donor lymphocytes in patients with high risk acute leukemia
Description: The purpose of this study is to determine if there is an increased in survival rate in patients who undergo a HCT transplantation followed by an infusion of genetically modified HSV-TK donor lymphocytes, compared to patients who have the standard HCT transplantation? with the standard infusion of he...MORE
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 Number: 201104236 Principal Investigator: Pusic, Iskra
Title: Longitudinal Study of Immune Mediated Disorders after Allogeneic Hematopoietic Cell Transplantation
Description: The purpose of this research study is to better understand the onset and course of GVHD and other immune mediated disorders after stem cell transplant by identifying and describing when these disorders happen, and the course they take . We also will collect specimens for future research studies....MORE
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 Number: 201209074 Principal Investigator: Dubberke, Erik
Title: A Phase 3b Multi-Center, Double-Blind, Randomized, Placebo Controlled Study to Demonstrate the Safety and Efficacy of Fidaxomicin for Prophylaxis against Clostridium difficile-Associated Diarrhea in Adults Undergoing Hematopoietic Stem Cell Transplantation
Description: The purpose of this research study is to determine if fidaxomicin is safe and effective in the prevention of clostridium difficile-associated diarrhea, or CDAD, compared with placebo. As there is currently no other drug on the market used to prevent CDAD before it occurs, the information obtained fr...MORE
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 Number: 201212113 Principal Investigator: Dubberke, Erik
Title: Evolution of CMV in Allogeneic Hematopoietic Cell Transplant Recipients
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