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Nobuo Horikoshi, PhD

660 S. Euclid Ave.
Campus Box 8224
St. Louis, MO 63110

Primary Academic Title:
Assistant Professor of Radiation Oncology, Division of Radiation and Cancer Biology, Washington University School of Medicine
Research Interest:
My long-term research focus is to develop protocols for effective radiation treatment of human cancer by establishing a detailed understanding of molecular recognition and function of p53 tumor suppressors in the processes of tumorigenesis. I am particularly interested in elucidating the involvement of mutant p53 in stress-response pathways. We aim to find a way of sensitizing cancer cells to irradiation or chemotherapy treatments, especially for cells carrying a mutation in p53 genes.
•1989: PhD, pharmaceutical sciences, University of Tokyo
•1989-1992: Research fellow, Wistar Institute of Anatomy and Biology, Philadelphia
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