This section of the Siteman Cancer Center Web site includes information about research advances made by Washington University School of Medicine investigators at Siteman. Recent advances are highlighted first, followed by a link to an archive of research-oriented press releases.
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New Test Will Help Physicians Deliver Personalized Breast Cancer Treatment
Feb. 9, 2009 – A set of 50 genes can be used to reliably identify the four known types of breast cancer, according to research conducted at the Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine and collaborating institutions. Using this 50-gene set, oncologists can potentially predict the most effective therapy for each breast tumor type and thereby personalize breast cancer treatment for all patients.
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Siteman Offers Clinical Trial of Investigational Drug for Pancreatic Cancer
Nov. 26, 2008 – The U.S. Food and Drug Administration (FDA) has approved a phase I clinical trial of the drug IMP321 in the treatment of advanced pancreatic cancer. The trial is being conducted by surgeon William Hawkins, MD, at the Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine.
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Washington University Scientists First to Sequence Genome of Cancer Patient
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| Acute myelogenous leukemia cells |
Nov. 5, 2008 -- For the first time, scientists have decoded the complete DNA of a cancer patient and traced her disease - acute myelogenous leukemia - to its genetic roots. A large research team at the Genome Sequencing Center and the Siteman Cancer Center at Washington University School of Medicine in St. Louis and Barnes-Jewish Hospital sequenced the genome of the patient - a woman in her 50s who ultimately died of her disease - and the genome of her leukemia cells, to identify genetic changes unique to her cancer. |
Genetic Region Linked to a Five Times Higher Lung Cancer Risk
Sept. 9, 2008 – A narrow region on chromosome 15 contains genetic variations strongly associated with familial lung cancer, says a study conducted by Washington University School of Medicine scientists at the Siteman Cancer Center and other institutions in the United States and the United Kingdom.
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Girls, Young Women Can Cut Risk of Early Breast Cancer Through Regular Exercise
May 13, 2008 -- Mothers, here's another reason to encourage your daughters to be physically active: Girls and young women who exercise regularly between the ages of 12 and 35 have a substantially lower risk of breast cancer before menopause compared to those who are less active, new research shows.
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| A tumor treated with fumagillin nanoparticles (left) is smaller than an untreated tumor. Nanoparticles containing an image enhancing metal (yellow) show that the treated tumor has much less blood vessel growth than the untreated tumor. |
Nano-sized Technology has Super-sized Effect on Tumors
April 2, 2008 -- Anyone facing chemotherapy would welcome an advance promising to dramatically reduce their dose of these often harsh drugs. Using nanotechnology, researchers at Washington University School of Medicine in St. Louis have taken a step closer to that goal.
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 Fugitive Cancer Cells Can Be Blocked by Stopping Blood Cells That Aid Them
March 6, 2008 -- Cancer cells get a helping hand from platelets, specialized blood cells involved in clotting. Platelets shelter and feed tumor cells that stray into the bloodstream, making it easier for cancer to spread, or metastasize. Research at the Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis suggests that inactivating platelets could slow down or prevent metastasis. |
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| Press Release Archive |
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