Share

CLINICAL TRIAL SEARCH RESULTS

NEW SEARCH
 Number: 201503060 Principal Investigator: Adkins, Douglas
Title: Phase II Trial of Mitomycin C in Patients with Incurable p16 Positive Oropharyngeal and p16 Negative Head and Neck Squamous Cell Carcinoma (HNSCC) Resistant to Platin, 5-FU, Cetuximab, and Taxane
Description: The purpose of this research study is to see how treatment with a drug called mitomycin C affects patients with head and neck cancer and to look at the side effects associated with treatment....MORE
___________________________________________________________________________________________________
 Number: 201412118 Principal Investigator: Uppaluri, Ravindra
Title: Immunotherapy with MK-3475 in locoregionally advanced, surgically resectable head and neck squamous cell carcinoma
Description: The purpose of this research study is look at a drug called pembrolizumab (MK-3475) and how well it treats head and neck cancer....MORE
___________________________________________________________________________________________________
 Number: 201410073 Principal Investigator: Adkins, Douglas
Title: Phase 2 Single Arm Trial of Cisplatin, Nab-Paclitaxel and Cetuximab (CACTUX) in Patients with Incurable HNSCC
Description: The purpose of this research study is to look at the effect of a treatment regimen called CACTUX, a combination of three drugs called cisplatin, nab-paclitaxel, and cetuximab on head and neck cancer....MORE
___________________________________________________________________________________________________
 Number: 201404139 Principal Investigator: Adkins, Douglas
Title: Phase I/II Trial of the Addition of PD 0332991 to Cetuximab in Patients with Incurable SCCHN
Description: The purpose of this research study is to find the maximum tolerated dose of a drug called palbociclib when given in combination with a drug called cetuximab, and to evaluate the side effects of this combination and look at how effective it is....MORE
___________________________________________________________________________________________________
 Number: 201211110 Principal Investigator: Adkins, Douglas
Title: A Phase I Trial of Pazopanib Suspension plus Cetuximab in Patients with Incurable Head and Neck Squamous Cell Carcinoma
Description: The purpose of this research study is to find the best dose of the study drug (pazopanib) in combination with cetuximab, as well as to see what the side effects of this treatment regimen are in patients with head and neck cancer....MORE
___________________________________________________________________________________________________
 Number: 201207059 Principal Investigator: Haughey, Bruce
Title: Adjuvant De-escalation, Extracapsular Spread, P16+, Transoral (A.D.E.P.T) Trial for Oropharynx Malignancy
Description: This research study is looking at cancer of the oropharynx (tonsil and/or base of the tongue) which has been shown to be related to the human papillomavirus (HPV) and which has lymph nodes showing extracapsular spread, meaning that the cancer in the lymph nodes is exposed to the soft tissue around ...MORE
___________________________________________________________________________________________________
 Number: RTOG 0920 Principal Investigator: Thorstad, Wade
Title: A Phase III Study of Postoperative Radiation Therapy (IMRT) +/- Cetuximab For Locally Advanced Resected Head and Neck Cancer
Description: The purpose of this study is to compare the effects, good and/or bad, of radiation therapy alone with radiation therapy and cetuximab on you and your cancer to find out which is better. In this study, you will get either radiation therapy alone OR radiation therapy and cetuximab. If you participate...MORE
___________________________________________________________________________________________________
 Number: NRG HN002 Principal Investigator: Thorstad, Wade
Title: A Randomized Phase II Trial for Patients with p16 Positive, Non-smoking Associated, Locoregionally Advanced Oropharyngeal Cancer (NRG-HN002)
Description: Previous studies of your type of cancer have shown high rates of cancer control but result in many short and long term side effects when treated with high dose radiation and chemotherapy. Recently, investigators have noticed similar high rates of cancer control in small numbers of patients who recei...MORE
___________________________________________________________________________________________________
 Number: CTSU NRG-HN001 Principal Investigator: Adkins, Douglas
Title: Randomized Phase II and Phase III Studies of Individualized Treatment for Nasopharyngeal Carcinoma Based on Biomarker Epstein Barr Virus (EBV) Deoxyribonucleic Acid (DNA)
Description: This study is being done to see how people with nasopharyngeal cancer respond to different types or levels of chemotherapy, based on the amount of Epstein Barr virus in their blood....MORE
___________________________________________________________________________________________________
 Number: CALGB A221304 Principal Investigator: Gay, Hiram
Title: A Phase III Placebo-Controlled, Randomized Three-Arm Study of Doxepin and a Topical Rinse in the Treatment of Acute Oral Mucositis Pain in Patients Receiving Radiotherapy with or without Chemotherapy
Description: This is a research study. We invite you to participate in this research study because you have been diagnosed with cancer and will be receiving radiation therapy to your head and neck. It is known that this type of radiation therapy can cause painful mouth sores, which can interfere with activities ...MORE
___________________________________________________________________________________________________
 Number: CALGB A091101 Principal Investigator: Adkins, Douglas
Title: CARBOPLATIN-PACLITAXEL INDUCTION CHEMOTHERAPY AND ABT-888 (VELIPARIB) –A PHASE 1/RANDOMIZED PHASE 2 STUDY IN PATIENTS WITH LOCOREGIONALLY ADVANCED SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK (A091101)
Description: The purpose of this research study is to find the highest safest dose of the investigational drug, ABT-888 (veliparib)when combined with chemotherapy that is given before combined chemotherapy and radiation therapy....MORE
___________________________________________________________________________________________________
 Number: 201505114 Principal Investigator: Adkins, Douglas
Title: A Phase 2 Proof-of-Concept Study of the Combination of ACP-196 and Pembrolizumab in Subjects with Advanced Head and Neck Squamous Cell Carcinoma
Description: The purpose of the study is to find out if the study drug, ACP-196 will slow or stop head and neck cancer from getting worse and whether the study drug causes side effects....MORE
___________________________________________________________________________________________________
 Number: 201504126 Principal Investigator: Adkins, Douglas
Title: A Phase II, Multi-Center, Single-Arm, Global Study of MEDI4736 Monotherapy in Patients with Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Description: The purpose of this research study is test the safety and effectiveness of an investigational anti-cancer drug called MEDI4736....MORE
___________________________________________________________________________________________________
 Number: 201409134 Principal Investigator: Adkins, Douglas
Title: A Phase III Randomized Trial of MK-3475 (Pembrolizumab) versus Standard Treatment in Subjects with Recurrent or Metastatic Head and Neck Cancer
Description: The purpose of this research study is to test the safety, tolerability and anti-tumor activity of the research study drug, pembrolizumab, compared to standard treatment (methotrexate, docetaxel or cetuximab) for recurrent or metastatic head and neck cancer....MORE
___________________________________________________________________________________________________
 Number: 201401078 Principal Investigator: Adkins, Douglas
Title: A phase Ib dose escalation/randomized phase II, multicenter, open-label study of BYL719 in combination with cetuximab in patients with recurrent or metastatic head and neck squamous cell carcinoma
Description: The purpose of this research study is to find out if the combination treatment of cetuximab and BYL719 is safe and has a beneficial effect in patients with head and neck cancer....MORE
___________________________________________________________________________________________________
 Number: 201308079 Principal Investigator: Adkins, Douglas
Title: A Randomized, Double-Blind, Placebo-Controlled Study of Chemotherapy Plus Cetuximab in Combination with VTX-2337 in Patients with Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
Description: The purpose of this research study is to compare the standard treatment to VTX-2337 added to the standard treatment to see if it helps tumors stop growing or shrink, and if it helps patients with squamous cell cancer of the head and neck live longer....MORE
___________________________________________________________________________________________________
 Number: ACRIN 6685 Principal Investigator: Nussenbaum, Brian
Title: PET/CT Staging of Head and Neck Cancer and its Impact on the N0 Neck Surgical Treatment
___________________________________________________________________________________________________
 Number: 201102323 Principal Investigator: Gay, Hiram
Title: Analysis of Histological, Genomic, Molecular, and Clinical Factors in Head and Neck Cancer: The Tissue Acquisition Protocol (TAP)
Description: The purpose of this research study is to discover genetic changes associated with cancer by documenting the DNA changes that occur in head and neck cancer cells. This may lead to better ways of preventing, detecting, and treating cancer and perhaps other diseases as well....MORE
___________________________________________________________________________________________________
 Number: 201111208 Principal Investigator: El-Mofty, Samir
Title: HPV-related squamous cell carcinoma of the head and neck skin in kidney transplant patients
___________________________________________________________________________________________________
 Number: 201105387 Principal Investigator: Haughey, Bruce
Title: Data Collection for Minimally Invasive, Endoscopic Head and Neck Cancer Surgery at Barnes-Jewish Hospital
___________________________________________________________________________________________________
 Number: 201407163 Principal Investigator: Govindan, Ramaswamy
Title: Open-Label, Dose-Escalation Trial to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Daily Oral MGCD265 Administered Without Interruption to Patients with Advanced Malignancies
Description: The goal of this clinical research study is to learn about safety of the drug MGCD265 and the effect that it has on cancer....MORE
___________________________________________________________________________________________________