Number: 201303043 Principal Investigator: Lockhart, A. Craig
Title: Phase II Study of Levocetirizine in Combination with Capecitabine + Bevacizumab to Overcome Resistance to Anti-angiogenic Therapy in Patients with Refractory Colorectal Cancer
Description: The purpose of this research study is to look at how adding a drug called levocetirizine to a standard treatment for colorectal cancer affects how the patient responds to the treatment, as well as looking at the side effects of this type of treatment....MORE
 Number: 201107017 Principal Investigator: Tan, Benjamin
Title: A Phase I Dose-Escalation Trial of Biweekly Intraperitoneal Oxaliplatin with Systemic Capecitabine and Bevacizumab Following Cytoreduction in Patients with Peritoneal Carcinomatosis from Appendiceal or Colorectal Cancer
Description: The main purpose of this research is to evaluate an intraperitoneal treatment for cancer following a surgical attempt to remove as much or all of the cancer as possible. The goals of this study are to determine the safety and side effects of this treatment, and to learn the maximum tolerated dose (...MORE
 Number: CALGB 80702 Principal Investigator: Tan, Benjamin
Title: A Phase III Trial of 6 versus 12 Treatments of Adjuvant FOLFOX plus Celecoxib or Placebo for Patients with Resected Stage III Colon Cancer
Description: In this study, we will evaluate the effects (good and bad) of an oral drug called celecoxib when given in combination with FOLFOX chemotherapy. ...MORE
 Number: 201212073 Principal Investigator: Tan, Benjamin
Title: STEAM (Sequencing Triplet with Avastin and Maintenance): Folfoxiri/Bevacizumab Regimens (Concurrent and Sequential) vs. Folfox/Bevacizumab in First-Line Metastatic Colorectal Cancer
Description: The purpose of this study is to find out what effects, good or bad, bevacizumab combined with different cancer drugs known as chemotherapy has on the patient and their metastatic colorectal cancer....MORE
 Number: 201202001 Principal Investigator: Zuckerman, Darryl
Title: A Phase III Clinical Trial Evaluating TheraSphere in Patients with Metastatic Colorectal Carcinoma of the Liver who have Failed First Line Chemotherapy
Description: The purpose of this research study is to examine whether adding treatment with TheraSphere early in the current standard for second-line chemotherapy treatment of metastatic colorectal cancer is better than the current treatment alone. Better means slowing or stopping the growth of liver tumors ...MORE
 Number: 201110005 Principal Investigator: James, Aimee
Title: Systems Intervention to Promote Colorectal Cancer Screening/ Program for the Elimination of Cancer Disparities
Description: The purpose of this part of the study is to understand people’s practices regarding health and cancer screening. You will be asked to talk with Dr. James or her designated staff member. We will ask questions about your background, your health and your thoughts and experiences about preventive care....MORE
 Number: 201309008 Principal Investigator: Deshpande, Anjali
Title: Examining Comorbidity Burden and Patient-Reported Outcomes of CRC Survivors
Description: The purpose of this research study is to understand how pre-existing chronic health conditions affect patient-reported outcomes such as cancer symptoms, treatment side-effects, physical and emotional functioning, and self-rated health among newly diagnosed colorectal cancer patients early in their t...MORE
 Number: 201301164 Principal Investigator: Liu, Ta-chiang
Title: Genetic, molecular, and pathologic analysis of colon cancer
 Number: 201107368 Principal Investigator: Nalbantoglu, ILKe
Title: LFAB and Colorectal Cancer
 Number: 201212057 Principal Investigator: Wise, Paul
Title: Cancer risks and mutation spectrum of mismatch repair gene mutations in African American families with Lynch syndrome
 Number: 201108327 Principal Investigator: Wang-Gillam, Andrea
Title: Phase I Study of Erlotinib and Temsirolimus in Resistant Solid Malignancies
Description: The purpose of this study is to determine the maximum tolerated dose and side effects of the combination of two drugs, temsirolimus and erlotinib, used to treat solid tumor cancers. Temsirolimus is approved by the Food and Drug Administration (FDA) for treatment of renal cancer and is considered inv...MORE
 Number: 201107068 Principal Investigator: Lockhart, A. Craig
Title: Phase I Safety and Pharmacokinetic Study of XRP6258 (Cabazitaxel) In Advanced Solid Tumor Patients with Varying Degrees of Hepatic Impairment
Description: The purpose of this study is to determine if Cabazitaxel is a safe treatment for patients with advanced cancers of different types who also have different levels of liver dysfunction. The highest safe dose of cabazitaxel (the maximum tolerated dose, or MTD) that can be given to patients with your le...MORE